DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg 85 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)NCCCN=[N]#N)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC):

85 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)NCCCN=[N]#N)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

highlighting its strong affinity and potential as a precision tool in targeted protein degradation studies

Product Name Phthalimidinoglutarimide-5'-propargyl-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C16H16ClN3O3 Molecular Weight 333

Product Name Lenalidomide-CO-PEG1-C2-amine HCl Synonyms Lenalidomide-4'-CO-PEG1-C2-amine HCl CAS Number n/a Related CAS Molecular Formula C18H23ClN4O5 Molecular Weight 410

Product Name Thalidomide-5'-O-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C21H25N5O8 Molecular Weight 475

DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg 85 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)NCCCN=[N]#N)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC):SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further